Published Applications Suddenly Need The RunOnce /AlternateShellStartup Logon Script to Load

[Travis MAIN NUMBER Rabe]

Starting Monday, some of my apps that I have not upgraded in months have stopped loading correctly.  I've tried deleting the user profiles and making them generate new ones.  I've tried making them logon with the Virtual Desktop first.  But the only thing that works is to gpedit.msc each VDA and add the user logon script of RunOnce AlternateShellStartup.

 

What can cause this to suddenly start to happen?  I did Windows updates last Thursday but only got word this week that this became an issue.  Any help would be greatly appreciated.